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Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice

BACKGROUND: Major depressive disorder is a widespread mood disorder. One of the most debilitating symptoms patients often experience is cognitive impairment. Recent findings suggest that inflammation is associated with depression and impaired cognition. Pro-inflammatory cytokines are elevated in the...

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Detalles Bibliográficos
Autores principales: Worthen, Ryan J., Garzon Zighelboim, Susan S., Torres Jaramillo, Camila S., Beurel, Eleonore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443292/
https://www.ncbi.nlm.nih.gov/pubmed/32828124
http://dx.doi.org/10.1186/s12974-020-01922-1