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Anti-inflammatory IL-10 administration rescues depression-associated learning and memory deficits in mice
BACKGROUND: Major depressive disorder is a widespread mood disorder. One of the most debilitating symptoms patients often experience is cognitive impairment. Recent findings suggest that inflammation is associated with depression and impaired cognition. Pro-inflammatory cytokines are elevated in the...
Autores principales: | Worthen, Ryan J., Garzon Zighelboim, Susan S., Torres Jaramillo, Camila S., Beurel, Eleonore |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443292/ https://www.ncbi.nlm.nih.gov/pubmed/32828124 http://dx.doi.org/10.1186/s12974-020-01922-1 |
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