Oral 25-Hydroxycholecalciferol Acts as an Agonist in the Duodenum of Mice and as Modeled in Cultured Human HT-29 and Caco2 Cells

BACKGROUND: 25-Hydroxycholecalciferol [25(OH)D] is the predominant circulating metabolite of vitamin D and serves as the precursor for 1α,25-dihydroxycholecalciferol [1,25(OH)(2)D], the hormonally active form. The presence of 1α-hydroxylase (1α-OHase) in the intestine suggests that 1,25(OH)(2)D can...

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Detalles Bibliográficos
Autores principales: Reynolds, Carmen J, Koszewski, Nicholas J, Horst, Ronald L, Beitz, Donald C, Goff, Jesse P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Biochemical, Molecular, and Genetic Mechanisms
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443726/
https://www.ncbi.nlm.nih.gov/pubmed/31665381
http://dx.doi.org/10.1093/jn/nxz261

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443726/
https://www.ncbi.nlm.nih.gov/pubmed/31665381
http://dx.doi.org/10.1093/jn/nxz261

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