Interleukin-1 receptor antagonist enhances chemosensitivity to fluorouracil in treatment of Kras mutant colon cancer

BACKGROUND: Kras mutant colon cancer shows abnormal activation of the nuclear factor kappa-B (NF-κB) pathway, resulting in the proliferation of tumor cells. Treatment with fluorouracil (5-FU) might not achieve the expected inhibition of proliferation of malignant cells based on the fluorouracil-indu...

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Detalles Bibliográficos
Autores principales: Yan, Yan, Lin, Hong-Wei, Zhuang, Zhuo-Nan, Li, Ming, Guo, Sen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Basic Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443842/
https://www.ncbi.nlm.nih.gov/pubmed/32879665
http://dx.doi.org/10.4251/wjgo.v12.i8.877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443842/
https://www.ncbi.nlm.nih.gov/pubmed/32879665
http://dx.doi.org/10.4251/wjgo.v12.i8.877

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