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Interleukin-1 receptor antagonist enhances chemosensitivity to fluorouracil in treatment of Kras mutant colon cancer
BACKGROUND: Kras mutant colon cancer shows abnormal activation of the nuclear factor kappa-B (NF-κB) pathway, resulting in the proliferation of tumor cells. Treatment with fluorouracil (5-FU) might not achieve the expected inhibition of proliferation of malignant cells based on the fluorouracil-indu...
| Autores principales: | , , , , |
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| 格式: | Online 文件 Texto |
| 语言: | English |
| 出版: |
Baishideng Publishing Group Inc
2020
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| 主题: | |
| 在线阅读: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443842/ https://www.ncbi.nlm.nih.gov/pubmed/32879665 http://dx.doi.org/10.4251/wjgo.v12.i8.877 |