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Longitudinal MEMRI analysis of brain phenotypes in a mouse model of Niemann-Pick Type C disease

Niemann-Pick Type C (NPC) is a rare genetic disorder characterized by progressive cell death in various tissues, particularly in the cerebellar Purkinje cells, with no known cure. Mouse models for human NPC have been generated and characterized histologically, behaviorally, and using longitudinal ma...

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Detalles Bibliográficos
Autores principales: Rallapalli, Harikrishna, Darwin, Benjamin C., Toro-Montoya, Estefania, Lerch, Jason P., Turnbull, Daniel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443857/
https://www.ncbi.nlm.nih.gov/pubmed/32417449
http://dx.doi.org/10.1016/j.neuroimage.2020.116894