GBAT: a gene-based association test for robust detection of trans-gene regulation

The observation that disease-associated genetic variants typically reside outside of exons has inspired widespread investigation into the genetic basis of transcriptional regulation. While associations between the mRNA abundance of a gene and its proximal SNPs (cis-eQTLs) are now readily identified,...

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Detalles Bibliográficos
Autores principales: Liu, Xuanyao, Mefford, Joel A., Dahl, Andrew, He, Yuan, Subramaniam, Meena, Battle, Alexis, Price, Alkes L., Zaitlen, Noah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444084/
https://www.ncbi.nlm.nih.gov/pubmed/32831138
http://dx.doi.org/10.1186/s13059-020-02120-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444084/
https://www.ncbi.nlm.nih.gov/pubmed/32831138
http://dx.doi.org/10.1186/s13059-020-02120-1

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