Cargando…

Forced expression of miR-143 and -145 in cardiomyocytes induces cardiomyopathy with a reductive redox shift

BACKGROUND: Animal model studies show that reductive stress is involved in cardiomyopathy and myopathy, but the exact physiological relevance remains unknown. In addition, the microRNAs miR-143 and miR-145 have been shown to be upregulated in cardiac diseases, but the underlying mechanisms associate...

Descripción completa

Detalles Bibliográficos
Autores principales: Ogawa, Kota, Noda, Akiko, Ueda, Jun, Ogata, Takehiro, Matsuyama, Rumiko, Nishizawa, Yuji, Qiao, Shanlou, Iwata, Satoru, Ito, Morihiro, Fujihara, Yoshitaka, Ichihara, Masatoshi, Adachi, Koichi, Takaoka, Yuji, Iwamoto, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444248/
https://www.ncbi.nlm.nih.gov/pubmed/32855642
http://dx.doi.org/10.1186/s11658-020-00232-x