A novel function of FAF1, which induces dopaminergic neuronal death through cell-to-cell transmission

BACKGROUND: Fas-associated factor 1 (FAF1) has been implicated in Parkinson’s disease (PD) and activates the cell death machinery in the cytosol. However, the presence of extracellular FAF1 has not been studied. METHODS: Serum-free conditioned medium (CM) from FAF1-transfected SH-SY5Y cells was conc...

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Detalles Bibliográficos
Autores principales: Park, Gyeongrin, Kim, Bok-Seok, Kim, Eunhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444258/
https://www.ncbi.nlm.nih.gov/pubmed/32831099
http://dx.doi.org/10.1186/s12964-020-00632-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444258/
https://www.ncbi.nlm.nih.gov/pubmed/32831099
http://dx.doi.org/10.1186/s12964-020-00632-8

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