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A novel function of FAF1, which induces dopaminergic neuronal death through cell-to-cell transmission
BACKGROUND: Fas-associated factor 1 (FAF1) has been implicated in Parkinson’s disease (PD) and activates the cell death machinery in the cytosol. However, the presence of extracellular FAF1 has not been studied. METHODS: Serum-free conditioned medium (CM) from FAF1-transfected SH-SY5Y cells was conc...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444258/ https://www.ncbi.nlm.nih.gov/pubmed/32831099 http://dx.doi.org/10.1186/s12964-020-00632-8 |