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How μ-Opioid Receptor Recognizes Fentanyl

In 2019, drug overdose has claimed over 70,000 lives in the United States. More than half of the deaths are related to synthetic opioids represented by fentanyl which is a potent agonist of mu-opioid receptor (mOR). In recent years, the crystal structures of mOR in complex with morphine derivatives...

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Detalles Bibliográficos
Autores principales: Vo, Quynh N., Mahinthichaichan, Paween, Shen, Jana, Ellis, Christopher R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444290/
https://www.ncbi.nlm.nih.gov/pubmed/32839778
http://dx.doi.org/10.1101/2020.08.16.253013