Mitochondria-associated protein LRPPRC exerts cardioprotective effects against doxorubicin-induced toxicity, potentially via inhibition of ROS accumulation

Doxorubicin (DOX) has been widely employed to treat cancer, particularly solid tumors and hematological malignancies, owing to its high efficacy; however, chemotherapy has been indicated to be cardiotoxic and induce adverse effects, including mitochondrial dysfunction and DNA damage, which limits it...

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Detalles Bibliográficos
Autores principales: Tang, Quan, Xiong, Wei, Ke, Xixian, Zhang, Jian, Xia, Yu, Liu, Daxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444327/
https://www.ncbi.nlm.nih.gov/pubmed/32855734
http://dx.doi.org/10.3892/etm.2020.9111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444327/
https://www.ncbi.nlm.nih.gov/pubmed/32855734
http://dx.doi.org/10.3892/etm.2020.9111

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