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Carnosic acid protects against pressure overload-induced cardiac remodelling by inhibiting the AKT/GSK3β/NOX4 signalling pathway

Oxidative stress and apoptosis serve an important role in the development of pressure overload-induced cardiac remodelling. Carnosic acid (CA) has been found to exert antioxidant and anti-apoptotic effects. The present study investigated the underlying mechanism of CA protection and whether this eff...

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Detalles Bibliográficos
Autores principales: Wei, Yun-Jie, Xu, Hai-Jun, Chen, Jia-Juan, Yang, Xi, Xiong, Jian, Wang, Jing, Cheng, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444384/
https://www.ncbi.nlm.nih.gov/pubmed/32855722
http://dx.doi.org/10.3892/etm.2020.9109