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High-dose TGF-β1 degrades human nucleus pulposus cells via ALK1-Smad1/5/8 activation
Transforming growth factor β1 (TGF-β1) can promote the proliferation and differentiation of intervertebral disc cells and participates in its repair process. However, whether TGF-β1 engages in the process of disc degeneration has not yet been fully elucidated. The present study aimed to investigate...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444386/ https://www.ncbi.nlm.nih.gov/pubmed/32855718 http://dx.doi.org/10.3892/etm.2020.9088 |