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Inhibition of Rho-kinase is involved in the therapeutic effects of atorvastatin in heart ischemia/reperfusion

The aim of the present study was to investigate the effects of atorvastatin against heart ischemia/reperfusion (I/R) injury and its potential underlying mechanism. Rats were allocated into the following groups: Sham, I/R, atorvastatin (10 mg/kg daily), fasudil (10 mg/kg daily) and atorvastatin + fas...

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Detalles Bibliográficos
Autores principales: Cheng, Chao, Liu, Xiao-Bo, Bi, Shao-Jie, Lu, Qing-Hua, Zhang, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444387/
https://www.ncbi.nlm.nih.gov/pubmed/32855683
http://dx.doi.org/10.3892/etm.2020.9070