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Hydrogen peroxide induces nucleus pulposus cell apoptosis by ATF4/CHOP signaling pathway

Oxidative stress induces excessive apoptosis resulting in the reduction of intervertebral disc cells, the consequent reduction of extracellular matrix (ECM) synthesis, and compositional changes, which is the pathological basis for intervertebral disc degeneration (IVDD). The present study explored t...

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Detalles Bibliográficos
Autor principal: Liu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444416/
https://www.ncbi.nlm.nih.gov/pubmed/32855694
http://dx.doi.org/10.3892/etm.2020.9052