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Hydrogen peroxide induces nucleus pulposus cell apoptosis by ATF4/CHOP signaling pathway
Oxidative stress induces excessive apoptosis resulting in the reduction of intervertebral disc cells, the consequent reduction of extracellular matrix (ECM) synthesis, and compositional changes, which is the pathological basis for intervertebral disc degeneration (IVDD). The present study explored t...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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D.A. Spandidos
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444416/ https://www.ncbi.nlm.nih.gov/pubmed/32855694 http://dx.doi.org/10.3892/etm.2020.9052 |