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Screening and evaluation of approved drugs as inhibitors of main protease of SARS-CoV-2

The COVID-19 pandemic caused by SARS-CoV-2 has emerged as a global catastrophe. The virus requires main protease for processing the viral polyproteins PP1A and PP1AB translated from the viral RNA. In search of a quick, safe and successful therapeutic agent; we screened various clinically approved dr...

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Detalles Bibliográficos
Autores principales: Tripathi, Praveen Kumar, Upadhyay, Saurabh, Singh, Manju, Raghavendhar, Siva, Bhardwaj, Mohit, Sharma, Pradeep, Patel, Ashok Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444494/
https://www.ncbi.nlm.nih.gov/pubmed/32853604
http://dx.doi.org/10.1016/j.ijbiomac.2020.08.166