Safety and parasite clearance of artemisinin-resistant Plasmodium falciparum infection: A pilot and a randomised volunteer infection study in Australia

BACKGROUND: Artemisinin resistance is threatening malaria control. We aimed to develop and test a human model of artemisinin-resistant (ART-R) Plasmodium falciparum to evaluate the efficacy of drugs against ART-R malaria. METHODS AND FINDINGS: We conducted 2 sequential phase 1, single-centre, open-l...

Descripción completa

Detalles Bibliográficos
Autores principales: Watts, Rebecca E., Odedra, Anand, Marquart, Louise, Webb, Lachlan, Abd-Rahman, Azrin N., Cascales, Laura, Chalon, Stephan, Rebelo, Maria, Pava, Zuleima, Collins, Katharine A., Pasay, Cielo, Chen, Nanhua, Peatey, Christopher L., Möhrle, Jörg J., McCarthy, James S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444516/
https://www.ncbi.nlm.nih.gov/pubmed/32822347
http://dx.doi.org/10.1371/journal.pmed.1003203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444516/
https://www.ncbi.nlm.nih.gov/pubmed/32822347
http://dx.doi.org/10.1371/journal.pmed.1003203

Ejemplares similares