JNK pathway restricts DENV2, ZIKV and CHIKV infection by activating complement and apoptosis in mosquito salivary glands

Arbovirus infection of Aedes aegypti salivary glands (SGs) determines transmission. However, there is a dearth of knowledge on SG immunity. Here, we characterized SG immune response to dengue, Zika and chikungunya viruses using high-throughput transcriptomics. We also describe a transcriptomic respo...

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Detalles Bibliográficos
Autores principales: Chowdhury, Avisha, Modahl, Cassandra M., Tan, Siok Thing, Wong Wei Xiang, Benjamin, Missé, Dorothée, Vial, Thomas, Kini, R. Manjunatha, Pompon, Julien Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444518/
https://www.ncbi.nlm.nih.gov/pubmed/32776975
http://dx.doi.org/10.1371/journal.ppat.1008754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444518/
https://www.ncbi.nlm.nih.gov/pubmed/32776975
http://dx.doi.org/10.1371/journal.ppat.1008754

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