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Endogenization and excision of human herpesvirus 6 in human genomes

Sequences homologous to human herpesvirus 6 (HHV-6) are integrated within the nuclear genome of about 1% of humans, but it is not clear how this came about. It is also uncertain whether integrated HHV-6 can reactivate into an infectious virus. HHV-6 integrates into telomeres, and this has recently b...

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Detalles Bibliográficos
Autores principales: Liu, Xiaoxi, Kosugi, Shunichi, Koide, Rie, Kawamura, Yoshiki, Ito, Jumpei, Miura, Hiroki, Matoba, Nana, Matsuzaki, Motomichi, Fujita, Masashi, Kamada, Anselmo Jiro, Nakagawa, Hidewaki, Tamiya, Gen, Matsuda, Koichi, Murakami, Yoshinori, Kubo, Michiaki, Aswad, Amr, Sato, Kei, Momozawa, Yukihide, Ohashi, Jun, Terao, Chikashi, Yoshikawa, Tetsushi, Parrish, Nicholas F., Kamatani, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444522/
https://www.ncbi.nlm.nih.gov/pubmed/32776928
http://dx.doi.org/10.1371/journal.pgen.1008915