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MrpH, a new class of metal-binding adhesin, requires zinc to mediate biofilm formation

Proteus mirabilis, a Gram-negative uropathogen, is a major causative agent in catheter-associated urinary tract infections (CAUTI). Mannose-resistant Proteus-like fimbriae (MR/P) are crucially important for P. mirabilis infectivity and are required for biofilm formation and auto-aggregation, as well...

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Detalles Bibliográficos
Autores principales: Jiang, Wangshu, Ubhayasekera, Wimal, Breed, Michael C., Norsworthy, Allison N., Serr, Nina, Mobley, Harry L. T., Pearson, Melanie M., Knight, Stefan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444556/
https://www.ncbi.nlm.nih.gov/pubmed/32780778
http://dx.doi.org/10.1371/journal.ppat.1008707