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Diabetes induced decreases in PKA signaling in cardiomyocytes: The role of insulin

The cAMP-dependent protein kinase (PKA) signaling pathway is the primary means by which the heart regulates moment-to-moment changes in contractility and metabolism. We have previously found that PKA signaling is dysfunctional in the diabetic heart, yet the underlying mechanisms are not fully unders...

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Detalles Bibliográficos
Autores principales: Eyster, Craig A., Matsuzaki, Satoshi, Newhardt, Maria F., Giorgione, Jennifer R., Humphries, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7444578/
https://www.ncbi.nlm.nih.gov/pubmed/32817622
http://dx.doi.org/10.1371/journal.pone.0231806