DAZL mediates a broad translational program regulating expansion and differentiation of spermatogonial progenitors

Fertility across metazoa requires the germline-specific DAZ family of RNA-binding proteins. Here we examine whether DAZL directly regulates progenitor spermatogonia using a conditional genetic mouse model and in vivo biochemical approaches combined with chemical synchronization of spermatogenesis. W...

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Detalles Bibliográficos
Autores principales: Mikedis, Maria M, Fan, Yuting, Nicholls, Peter K, Endo, Tsutomu, Jackson, Emily K, Cobb, Sarah A, de Rooij, Dirk G, Page, David C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445011/
https://www.ncbi.nlm.nih.gov/pubmed/32686646
http://dx.doi.org/10.7554/eLife.56523

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445011/
https://www.ncbi.nlm.nih.gov/pubmed/32686646
http://dx.doi.org/10.7554/eLife.56523

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