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Intranasal delivery of mesenchymal stem cell‐derived extracellular vesicles exerts immunomodulatory and neuroprotective effects in a 3xTg model of Alzheimer's disease

The critical role of neuroinflammation in favoring and accelerating the pathogenic process in Alzheimer's disease (AD) increased the need to target the cerebral innate immune cells as a potential therapeutic strategy to slow down the disease progression. In this scenario, mesenchymal stem cells...

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Detalles Bibliográficos
Autores principales: Losurdo, Morris, Pedrazzoli, Matteo, D'Agostino, Claudia, Elia, Chiara A., Massenzio, Francesca, Lonati, Elena, Mauri, Mario, Rizzi, Laura, Molteni, Laura, Bresciani, Elena, Dander, Erica, D'Amico, Giovanna, Bulbarelli, Alessandra, Torsello, Antonio, Matteoli, Michela, Buffelli, Mario, Coco, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445021/
https://www.ncbi.nlm.nih.gov/pubmed/32496649
http://dx.doi.org/10.1002/sctm.19-0327