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Analysis of the transgene insertion pattern in a transgenic mouse strain using long-read sequencing

Transgene insertion patterns are critical for the analysis of transgenic animals because the influence of transgenes may change depending on the insertion pattern (such as copy numbers and orientations of concatenations) and the insertion position in the genome. We previously reported a genomic walk...

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Detalles Bibliográficos
Autores principales: Suzuki, Osamu, Koura, Minako, Uchio-Yamada, Kozue, Sasaki, Mitsuho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445054/
https://www.ncbi.nlm.nih.gov/pubmed/32051389
http://dx.doi.org/10.1538/expanim.19-0118