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Thy1 promoter activity in the Rosa26 locus in mice: lessons from Dre-rox conditional expression system

The pronuclear injection (PI)-based targeted transgenesis (PITT) method allows the generation of targeted transgenic (Tg) mice wherein a single copy of a transgene is integrated into the Rosa26 locus following PI. The Rosa26 locus allows unbiased ubiquitous expression of integrated transgenes; howev...

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Detalles Bibliográficos
Autores principales: Tamura, Saaki, Yasuoka, Yukiko, Miura, Hiromi, Takahashi, Gou, Sato, Masahiro, Ohtsuka, Masato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Association for Laboratory Animal Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445056/
https://www.ncbi.nlm.nih.gov/pubmed/32051391
http://dx.doi.org/10.1538/expanim.20-0002