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Thy1 promoter activity in the Rosa26 locus in mice: lessons from Dre-rox conditional expression system
The pronuclear injection (PI)-based targeted transgenesis (PITT) method allows the generation of targeted transgenic (Tg) mice wherein a single copy of a transgene is integrated into the Rosa26 locus following PI. The Rosa26 locus allows unbiased ubiquitous expression of integrated transgenes; howev...
Autores principales: | Tamura, Saaki, Yasuoka, Yukiko, Miura, Hiromi, Takahashi, Gou, Sato, Masahiro, Ohtsuka, Masato |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Association for Laboratory Animal Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445056/ https://www.ncbi.nlm.nih.gov/pubmed/32051391 http://dx.doi.org/10.1538/expanim.20-0002 |
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