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Integration of postmortem amygdala expression profiling, GWAS, and functional cell culture assays: neuroticism-associated synaptic vesicle glycoprotein 2A (SV2A) gene is regulated by miR-133a and miR-218

Recent genome-wide studies have begun to identify gene variants, expression profiles, and regulators associated with neuroticism, anxiety disorders, and depression. We conducted a set of experimental cell culture studies of gene regulation by micro RNAs (miRNAs), based on genome-wide transcriptome,...

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Detalles Bibliográficos
Autores principales: Jurkiewicz, Magdalena, Moser, Dirk, Koller, Antonius, Yu, Lei, Chen, Emily I., Bennett, David A., Canli, Turhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445165/
https://www.ncbi.nlm.nih.gov/pubmed/32839459
http://dx.doi.org/10.1038/s41398-020-00966-4