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NEDDylation negatively regulates ERRβ expression to promote breast cancer tumorigenesis and progression

Estrogen-related receptor beta (ERRβ) is downregulated in breast cancer cells and its overexpression in breast cancer patients is positively correlated with an improved prognosis and prolonged relapse-free survival. Here, we unravelled a molecular mechanism for ERRβ downregulation in breast cancer....

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Detalles Bibliográficos
Autores principales: Naik, Sanoj K., Lam, Eric W.-F., Parija, Monalisa, Prakash, Surya, Jiramongkol, Yannasittha, Adhya, Amit K., Parida, Dilip K., Mishra, Sandip K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445179/
https://www.ncbi.nlm.nih.gov/pubmed/32839427
http://dx.doi.org/10.1038/s41419-020-02838-7