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NRIP3 upregulation confers resistance to chemoradiotherapy in ESCC via RTF2 removal by accelerating ubiquitination and degradation of RTF2

Esophageal squamous cell carcinoma (ESCC) is a common malignant cancer worldwide. Despite recent improvements in surgical techniques and adjuvant therapies, the prognosis of patients with advanced ESCC remains poor. Resistance to chemoradiotherapy (CRT) remains a major cause of treatment failure for...

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Detalles Bibliográficos
Autores principales: Suo, Daqin, Wang, Ling, Zeng, Tingting, Zhang, Hui, Li, Lei, Liu, Jinyun, Yun, Jingping, Guan, Xin-Yuan, Li, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445249/
https://www.ncbi.nlm.nih.gov/pubmed/32839439
http://dx.doi.org/10.1038/s41389-020-00260-4