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Targeting of intracellular Ca(2+) stores as a therapeutic strategy against age-related neurotoxicities

Calcium dysregulation often underlies pathologies associated with aging and age-associated neurodegenerative diseases. Cells express a unique pattern of Ca(2+) channels and pumps geared to fulfill specific physiological requirements and there is a decline in the fidelity of these processes with age...

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Detalles Bibliográficos
Autores principales: Goldberg, Joshua, Currais, Antonio, Ates, Gamze, Huang, Ling, Shokhirev, Maxim, Maher, Pamela, Schubert, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445274/
https://www.ncbi.nlm.nih.gov/pubmed/32884834
http://dx.doi.org/10.1038/s41514-020-00048-1