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Ischemia reperfusion injury provokes adverse left ventricular remodeling in dysferlin-deficient hearts through a pathway that involves TIRAP dependent signaling

Cardiac myocytes have multiple cell autonomous mechanisms that facilitate stabilization and repair of damaged sarcolemmal membranes following myocardial injury. Dysferlin is a protein which facilitates membrane repair by promoting membrane resealing. Although prior studies have shown that dysferlin-...

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Detalles Bibliográficos
Autores principales: Evans, Sarah, Weinheimer, Carla J., Kovacs, Attila, Williams, Jesse W., Randolph, Gwendalyn J., Jiang, Wenlong, Barger, Philip M., Mann, Douglas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445276/
https://www.ncbi.nlm.nih.gov/pubmed/32839504
http://dx.doi.org/10.1038/s41598-020-71079-7