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Ischemia reperfusion injury provokes adverse left ventricular remodeling in dysferlin-deficient hearts through a pathway that involves TIRAP dependent signaling
Cardiac myocytes have multiple cell autonomous mechanisms that facilitate stabilization and repair of damaged sarcolemmal membranes following myocardial injury. Dysferlin is a protein which facilitates membrane repair by promoting membrane resealing. Although prior studies have shown that dysferlin-...
Autores principales: | Evans, Sarah, Weinheimer, Carla J., Kovacs, Attila, Williams, Jesse W., Randolph, Gwendalyn J., Jiang, Wenlong, Barger, Philip M., Mann, Douglas L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445276/ https://www.ncbi.nlm.nih.gov/pubmed/32839504 http://dx.doi.org/10.1038/s41598-020-71079-7 |
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