USP7 negatively controls global DNA methylation by attenuating ubiquitinated histone-dependent DNMT1 recruitment

Previous studies have implicated an essential role for UHRF1-mediated histone H3 ubiquitination in recruiting DNMT1 to replication sites for DNA maintenance methylation during S phase of the cell cycle. However, the regulatory mechanism on UHRF1-mediated histone ubiquitination is not clear. Here we...

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Detalles Bibliográficos
Autores principales: Li, Jialun, Wang, Ruiping, Jin, Jianyu, Han, Mengmeng, Chen, Zhaosu, Gao, Yingying, Hu, Xueli, Zhu, Haijun, Gao, Huifang, Lu, Kongbin, Shao, Yanjiao, Lyu, Cong, Lai, Weiyi, Li, Pishun, Hu, Guang, Li, Jiwen, Li, Dali, Wang, Hailin, Wu, Qihan, Wong, Jiemin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445300/
https://www.ncbi.nlm.nih.gov/pubmed/32884836
http://dx.doi.org/10.1038/s41421-020-00188-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445300/
https://www.ncbi.nlm.nih.gov/pubmed/32884836
http://dx.doi.org/10.1038/s41421-020-00188-4

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