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Morroniside attenuates high glucose–induced BMSC dysfunction by regulating the Glo1/AGE/RAGE axis

OBJECTIVES: High glucose (HG)–mediated bone marrow mesenchymal stem cell (BMSC) dysfunction plays a key role in impaired bone formation induced by type 1 diabetes mellitus (T1DM). Morroniside is an iridoid glycoside derived from the Chinese herb Cornus officinalis, and it has abundant biological act...

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Detalles Bibliográficos
Autores principales: Sun, Yi, Zhu, Yu, Liu, Xuanzhe, Chai, Yimin, Xu, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445400/
https://www.ncbi.nlm.nih.gov/pubmed/32643284
http://dx.doi.org/10.1111/cpr.12866