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Expanding the toolbox of synthetic riboswitches with guanine-dependent aptazymes

Artificial riboswitches based on ribozymes serve as versatile tools for ligand-dependent gene expression regulation. Advantages of these so-called aptazymes are their modular architecture and the comparably little coding space they require. A variety of aptamer-ribozyme combinations were constructed...

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Detalles Bibliográficos
Autores principales: Stifel, Julia, Spöring, Maike, Hartig, Jörg Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445771/
https://www.ncbi.nlm.nih.gov/pubmed/32995528
http://dx.doi.org/10.1093/synbio/ysy022