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Expanding the toolbox of synthetic riboswitches with guanine-dependent aptazymes
Artificial riboswitches based on ribozymes serve as versatile tools for ligand-dependent gene expression regulation. Advantages of these so-called aptazymes are their modular architecture and the comparably little coding space they require. A variety of aptamer-ribozyme combinations were constructed...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445771/ https://www.ncbi.nlm.nih.gov/pubmed/32995528 http://dx.doi.org/10.1093/synbio/ysy022 |