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Natural polyphenol assisted delivery of single-strand oligonucleotides by cationic polymers

Single-strand oligonucleotides provide promising potential as new therapeutics towards various diseases. However, the efficient delivery of oligonucleotide therapeutics is still challenging due to their susceptibility to nuclease degradation and the lack of effective carriers for condensation. In th...

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Detalles Bibliográficos
Autores principales: Shen, Wanwan, Wang, Ruojun, Fan, Qianqian, Li, Yiwen, Cheng, Yiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445782/
https://www.ncbi.nlm.nih.gov/pubmed/32366887
http://dx.doi.org/10.1038/s41434-020-0151-y