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Recent development of AAV-based gene therapies for inner ear disorders

Gene therapy for auditory diseases is gradually maturing. Recent progress in gene therapy treatments for genetic and acquired hearing loss has demonstrated the feasibility in animal models. However, a number of hurdles, such as lack of safe viral vector with high efficiency and specificity, robust d...

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Detalles Bibliográficos
Autores principales: Lan, Yiyang, Tao, Yong, Wang, Yunfeng, Ke, Junzi, Yang, Qiuxiang, Liu, Xiaoyi, Su, Bing, Wu, Yiling, Lin, Chao-Po, Zhong, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445886/
https://www.ncbi.nlm.nih.gov/pubmed/32424232
http://dx.doi.org/10.1038/s41434-020-0155-7