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The two faces of synaptic failure in App(NL-G-F) knock-in mice

BACKGROUND: Intensive basic and preclinical research into Alzheimer’s disease (AD) has yielded important new findings, but they could not yet been translated into effective therapies. One of the reasons is the lack of animal models that sufficiently reproduce the complexity of human AD and the respo...

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Detalles Bibliográficos
Autores principales: Latif-Hernandez, Amira, Sabanov, Victor, Ahmed, Tariq, Craessaerts, Katleen, Saito, Takashi, Saido, Takaomi, Balschun, Detlef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445922/
https://www.ncbi.nlm.nih.gov/pubmed/32838792
http://dx.doi.org/10.1186/s13195-020-00667-6