Endogenous asymmetric dimethylarginine accumulation contributes to the suppression of myocardial mitochondrial biogenesis in type 2 diabetic rats

BACKGROUND: Suppressed mitochondrial biosynthesis has been reported to be the early signal of mitochondrial dysfunction which contributes to diabetic cardiomyopathy, but the mechanism of mitochondrial biosynthesis suppression is unclear. Nitric oxide synthase inhibitor asymmetric dimethylarginine (A...

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Detalles Bibliográficos
Autores principales: Xiong, Yan, Hai, Chun-Xia, Fang, Wei-Jin, Lei, Yan-Ping, Li, Xiao-Mei, Zhou, Xin-Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445927/
https://www.ncbi.nlm.nih.gov/pubmed/32855652
http://dx.doi.org/10.1186/s12986-020-00486-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7445927/
https://www.ncbi.nlm.nih.gov/pubmed/32855652
http://dx.doi.org/10.1186/s12986-020-00486-4

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