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Epigenetic silencing of long non-coding RNA BM742401 in multiple myeloma: impact on prognosis and myeloma dissemination
BACKGROUND: Long non-coding RNA (lncRNA) BM742401 is a tumor suppressor in gastric cancer and chronic lymphocytic leukemia. As the promoter and coding region of BM742401 are fully embedded in a CpG island, we hypothesized that BM742401 is a tumor suppressor lncRNA epigenetically silenced by promoter...
Autores principales: | Li, Zhenhai, Kumar, Shaji, Jin, Dong-Yan, Calin, George A., Chng, Wee-Joo, Siu, Kam-Leung, Poon, Ming-Wai, Chim, Chor Sang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446116/ https://www.ncbi.nlm.nih.gov/pubmed/32855620 http://dx.doi.org/10.1186/s12935-020-01504-4 |
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