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Vulvar Squamous Cell Carcinoma: Comprehensive Genomic Profiling of HPV+ Versus HPV– Forms Reveals Distinct Sets of Potentially Actionable Molecular Targets

PURPOSE: Vulvar squamous cell carcinoma (vSCC) encompasses two predominant variants: one associated with detectable high-risk strains of human papillomavirus (hrHPV) and a second form often occurring in the context of chronic dermatitis in postmenopausal women. Genomic assessment of a large-scale co...

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Detalles Bibliográficos
Autores principales: Williams, Erik A., Werth, Adrienne J., Sharaf, Radwa, Montesion, Meagan, Sokol, Ethan S., Pavlick, Dean C., McLaughlin-Drubin, Molly, Erlich, Rachel, Toma, Helen, Williams, Kevin Jon, Venstrom, Jeff M., Alexander, Brian M., Shah, Nikunj, Danziger, Natalie, Hemmerich, Amanda C., Severson, Eric A., Killian, Jonathan Keith, Lin, Douglas I., Ross, Jeffrey S., Tse, Julie Y., Ramkissoon, Shakti H., Mochel, Mark C., Elvin, Julia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446361/
https://www.ncbi.nlm.nih.gov/pubmed/32923875
http://dx.doi.org/10.1200/PO.19.00406