Cargando…

Vulvar Squamous Cell Carcinoma: Comprehensive Genomic Profiling of HPV+ Versus HPV– Forms Reveals Distinct Sets of Potentially Actionable Molecular Targets

PURPOSE: Vulvar squamous cell carcinoma (vSCC) encompasses two predominant variants: one associated with detectable high-risk strains of human papillomavirus (hrHPV) and a second form often occurring in the context of chronic dermatitis in postmenopausal women. Genomic assessment of a large-scale co...

Descripción completa

Detalles Bibliográficos
Autores principales:	Williams, Erik A., Werth, Adrienne J., Sharaf, Radwa, Montesion, Meagan, Sokol, Ethan S., Pavlick, Dean C., McLaughlin-Drubin, Molly, Erlich, Rachel, Toma, Helen, Williams, Kevin Jon, Venstrom, Jeff M., Alexander, Brian M., Shah, Nikunj, Danziger, Natalie, Hemmerich, Amanda C., Severson, Eric A., Killian, Jonathan Keith, Lin, Douglas I., Ross, Jeffrey S., Tse, Julie Y., Ramkissoon, Shakti H., Mochel, Mark C., Elvin, Julia A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Clinical Oncology 2020
Materias:	Original Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446361/ https://www.ncbi.nlm.nih.gov/pubmed/32923875 http://dx.doi.org/10.1200/PO.19.00406

Ejemplares similares

CYLD-mutant cylindroma-like basaloid carcinoma of the anus: a genetically and morphologically distinct class of HPV-related anal carcinoma
por: Williams, Erik A., et al.
Publicado: (2020)

Melanoma with in-frame deletion of MAP2K1: a distinct molecular subtype of cutaneous melanoma mutually exclusive from BRAF, NRAS, and NF1 mutations
por: Williams, Erik A., et al.
Publicado: (2020)

Melanomas with activating RAF1 fusions: clinical, histopathologic, and molecular profiles
por: Williams, Erik A., et al.
Publicado: (2020)

CDKN2C-Null Leiomyosarcoma: A Novel, Genomically Distinct Class of TP53/RB1–Wild-Type Tumor With Frequent CIC Genomic Alterations and 1p/19q-Codeletion
por: Williams, Erik A., et al.
Publicado: (2020)

CYLD mutation characterizes a subset of HPV-positive head and neck squamous cell carcinomas with distinctive genomics and frequent cylindroma-like histologic features
por: Williams, Erik A., et al.
Publicado: (2020)

HPV51-associated Leiomyosarcoma: A Novel Class of TP53/RB1-Wildtype Tumor With Predilection for the Female Lower Reproductive Tract
por: Williams, Erik A., et al.
Publicado: (2022)

HPV prevalence in vulvar cancer in Austria
por: Pils, Sophie, et al.
Publicado: (2017)

HPV-associated vulvar carcinoma with sebaceous differentiation
por: Kuan, Irena, et al.
Publicado: (2023)

Molecular profiling of mesonephric and mesonephric-like carcinomas of cervical, endometrial and ovarian origin
por: Lin, Douglas I., et al.
Publicado: (2020)

Genomic landscape of non‐small‐cell lung cancer with methylthioadenosine phosphorylase (MTAP) deficiency
por: Ashok Kumar, Prashanth, et al.
Publicado: (2022)

Digital droplet PCR-based quantification of ccfHPV-DNA as liquid biopsy in HPV-driven cervical and vulvar cancer
por: Thangarajah, Fabinshy, et al.
Publicado: (2023)

A Very Rare Case: HPV-Negative Vulvar Cancer in an Adolescent
por: Kahramanoglu, Ilker, et al.
Publicado: (2018)

HPV16 viral characteristics in primary, recurrent and metastatic vulvar carcinoma
por: Lillsunde Larsson, Gabriella, et al.
Publicado: (2018)

p16 in HPV-associated cancers
por: Munger, Karl, et al.
Publicado: (2013)

Genomic Profiling of Circulating Tumor DNA From Cerebrospinal Fluid to Guide Clinical Decision Making for Patients With Primary and Metastatic Brain Tumors
por: Ramkissoon, Lori A., et al.
Publicado: (2020)

Epithelial-mesenchymal transition-like events in vulvar cancer and its relation with HPV
por: Rodrigues, I S, et al.
Publicado: (2013)

Surgical Treatment of Vulvar HSIL: Adjuvant HPV Vaccine Reduces Recurrent Disease
por: Ghelardi, Alessandro, et al.
Publicado: (2021)

Global availability of data on HPV genotype-distribution in cervical, vulvar and vaginal disease and genotype-specific prevalence and incidence of HPV infection in females
por: Wagner, Monika, et al.
Publicado: (2015)

Landscape of Biomarkers in Non-small Cell Lung Cancer Using Comprehensive Genomic Profiling and PD-L1 Immunohistochemistry
por: Huang, Richard S. P., et al.
Publicado: (2021)

Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer
por: Sivapiragasam, Abirami, et al.
Publicado: (2020)

Vulvar Buschke-Löwenstein tumor in a HPV 16 infected woman: case report
por: Ernez, Safia, et al.
Publicado: (2022)

A pan-cancer landscape of telomeric content shows that RAD21 and HGF alterations are associated with longer telomeres
por: Sharaf, Radwa, et al.
Publicado: (2022)

FoundationOne CDx testing accurately determines whole arm 1p19q codeletion status in gliomas
por: Sharaf, Radwa, et al.
Publicado: (2021)

Erratum to: FoundationOne CDx testing accurately determines whole arm 1p19q codeletion status in gliomas
por: Sharaf, Radwa, et al.
Publicado: (2021)

Distribution of HPV types associated with cervical cancers in Scotland and implications for the impact of HPV vaccines
por: Cuschieri, K, et al.
Publicado: (2010)

Evolution and Taxonomic Classification of Alphapapillomavirus 7 Complete Genomes: HPV18, HPV39, HPV45, HPV59, HPV68 and HPV70
por: Chen, Zigui, et al.
Publicado: (2013)

Evolution and Taxonomic Classification of Human Papillomavirus 16 (HPV16)-Related Variant Genomes: HPV31, HPV33, HPV35, HPV52, HPV58 and HPV67
por: Chen, Zigui, et al.
Publicado: (2011)

An investigation into human papillomavirus (HPV) vaccination for patients undergoing surgery for high-grade cervical or vulvar dysplasia
por: Boyles, Glenn P., et al.
Publicado: (2022)

The First Human Vulvar Intraepithelial Neoplasia Cell Line with Naturally Infected Episomal HPV18 Genome
por: Wu, Ming, et al.
Publicado: (2022)

Efficacy of HPV Vaccination Regarding Vulvar and Vaginal Recurrences in Previously Treated Women: The Need for Further Evidence
por: Bechini, Angela, et al.
Publicado: (2023)

Medical students’ knowledge of HPV, HPV vaccine, and HPV-associated head and neck cancer
por: Du, Eric Y., et al.
Publicado: (2022)

HPV vaccination bridges to HPV screening
por: Harper, Diane M, et al.
Publicado: (2020)

Special Issue: HPV and HPV Vaccines
por: Hibma, Merilyn
Publicado: (2022)

Clinically Advanced Pheochromocytomas and Paragangliomas: A Comprehensive Genomic Profiling Study
por: Bratslavsky, Gennady, et al.
Publicado: (2021)

Prevalence of High-Risk Nonvaccine Human Papillomavirus Types in Advanced Squamous Cell Carcinoma Among Individuals of African vs Non-African Ancestry
por: Williams, Erik A., et al.
Publicado: (2021)

150 Carcinogenesis of HPV
por: Buonaguro, FM, et al.
Publicado: (2014)

Molecular Detection Methods in HPV-Related Cancers
por: Williams, Jordana, et al.
Publicado: (2022)

Community socioeconomic status and rural/racial disparities in HPV−/+ head and neck cancer
por: Semprini, Jason, et al.
Publicado: (2023)

Localized amyloidosis in usual-type vulvar intraepithelial neoplasia: High-risk HPV association and potential clinical significance. A series of 45 cases
por: Sadeq Islam, K.M., et al.
Publicado: (2021)

HPV prevalence and HPV-related dysplasia in elderly women
por: Hermansson, Ruth S., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_tgiaac9ialt3csle8e4u9in4hn