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Genomic Resistance Patterns to Second-Generation Androgen Blockade in Paired Tumor Biopsies of Metastatic Castration-Resistant Prostate Cancer
PURPOSE: Patients with castration-resistant prostate cancer (CRPC) receive second-generation androgen-deprivation therapy, but frequently experience relapse or do not respond. Understanding the genetic mechanisms of resistance will help to identify strategies and biomarkers that are essential for th...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Clinical Oncology
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446377/ https://www.ncbi.nlm.nih.gov/pubmed/32913968 http://dx.doi.org/10.1200/PO.17.00140 |