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Window-of-Opportunity Study of Valproic Acid in Breast Cancer Testing a Gene Expression Biomarker

PURPOSE: The anticancer activity of valproic acid (VPA) is attributed to the inhibition of histone deacetylase. We previously published the genomically derived sensitivity signature for VPA (GDSS-VPA), a gene expression biomarker that predicts breast cancer sensitivity to VPA in vitro and in vivo. W...

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Detalles Bibliográficos
Autores principales: Cohen, Adam L., Neumayer, Leigh, Boucher, Ken, Factor, Rachel E., Shrestha, Gajendra, Wade, Mark, Lamb, John G., Arbogast, Kylee, Piccolo, Stephen R., Riegert, Joanna, Schabel, Matthias, Bild, Andrea H., Werner, Theresa L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446454/
https://www.ncbi.nlm.nih.gov/pubmed/32913974
http://dx.doi.org/10.1200/PO.16.00011