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Immunological Differences Between Immune-Rich Estrogen Receptor–Positive and Immune-Rich Triple-Negative Breast Cancers

PURPOSE: A subset of estrogen receptor–positive (ER-positive) breast cancer (BC) contains high levels of tumor-infiltrating lymphocytes (TILs), similar to triple-negative BC (TNBC). The majority of immuno-oncology trials target TNBCs because of the greater proportion of TIL-rich TNBCs. The extent to...

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Detalles Bibliográficos
Autores principales: O’Meara, Tess, Marczyk, Michal, Qing, Tao, Yaghoobi, Vesal, Blenman, Kim, Cole, Kimberly, Pelekanou, Vasiliki, Rimm, David L., Pusztai, Lajos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Clinical Oncology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446500/
https://www.ncbi.nlm.nih.gov/pubmed/32923897
http://dx.doi.org/10.1200/PO.19.00350