Age and the association between apolipoprotein E genotype and Alzheimer disease: A cerebrospinal fluid biomarker–based case–control study

BACKGROUND: The ε4 allele of apolipoprotein E (APOE) gene and increasing age are two of the most important known risk factors for developing Alzheimer disease (AD). The diagnosis of AD based on clinical symptoms alone is known to have poor specificity; recently developed diagnostic criteria based on...

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Detalles Bibliográficos
Autores principales: Saddiki, Hana, Fayosse, Aurore, Cognat, Emmanuel, Sabia, Séverine, Engelborghs, Sebastiaan, Wallon, David, Alexopoulos, Panagiotis, Blennow, Kaj, Zetterberg, Henrik, Parnetti, Lucilla, Zerr, Inga, Hermann, Peter, Gabelle, Audrey, Boada, Mercè, Orellana, Adelina, de Rojas, Itziar, Lilamand, Matthieu, Bjerke, Maria, Van Broeckhoven, Christine, Farotti, Lucia, Salvadori, Nicola, Diehl-Schmid, Janine, Grimmer, Timo, Hourregue, Claire, Dugravot, Aline, Nicolas, Gaël, Laplanche, Jean-Louis, Lehmann, Sylvain, Bouaziz-Amar, Elodie, Hugon, Jacques, Tzourio, Christophe, Singh-Manoux, Archana, Paquet, Claire, Dumurgier, Julien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446786/
https://www.ncbi.nlm.nih.gov/pubmed/32817639
http://dx.doi.org/10.1371/journal.pmed.1003289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446786/
https://www.ncbi.nlm.nih.gov/pubmed/32817639
http://dx.doi.org/10.1371/journal.pmed.1003289

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