Primate lentiviruses require Inositol hexakisphosphate (IP6) or inositol pentakisphosphate (IP5) for the production of viral particles

Inositol hexakisphosphate (IP6) potently stimulates HIV-1 particle assembly in vitro and infectious particle production in vivo. However, knockout cells lacking inositol-pentakisphosphate 2-kinase (IPPK-KO), the enzyme that produces IP6 by phosphorylation of inositol pentakisphosphate (IP5), were st...

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Detalles Bibliográficos
Autores principales: Ricana, Clifton L., Lyddon, Terri D., Dick, Robert A., Johnson, Marc C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446826/
https://www.ncbi.nlm.nih.gov/pubmed/32776974
http://dx.doi.org/10.1371/journal.ppat.1008646

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446826/
https://www.ncbi.nlm.nih.gov/pubmed/32776974
http://dx.doi.org/10.1371/journal.ppat.1008646

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