The auxiliary subunit KCNE1 regulates KCNQ1 channel response to sustained calcium-dependent PKC activation

The slow cardiac delayed rectifier current (IKs) is formed by KCNQ1 and KCNE1 subunits and is one of the major repolarizing currents in the heart. Decrease of IKs currents either due to inherited mutations or pathological remodeling is associated with increased risk for cardiac arrhythmias and sudde...

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Detalles Bibliográficos
Autores principales: Xu Parks, Xiaorong, Qudsi, Haani, Braun, Chen, Lopes, Coeli M. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446858/
https://www.ncbi.nlm.nih.gov/pubmed/32833978
http://dx.doi.org/10.1371/journal.pone.0237591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446858/
https://www.ncbi.nlm.nih.gov/pubmed/32833978
http://dx.doi.org/10.1371/journal.pone.0237591

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