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Rho factor mediates flagellum and toxin phase variation and impacts virulence in Clostridioides difficile
The intestinal pathogen Clostridioides difficile exhibits heterogeneity in motility and toxin production. This phenotypic heterogeneity is achieved through phase variation by site-specific recombination via the DNA recombinase RecV, which reversibly inverts the “flagellar switch” upstream of the flg...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446863/ https://www.ncbi.nlm.nih.gov/pubmed/32785266 http://dx.doi.org/10.1371/journal.ppat.1008708 |