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Rho factor mediates flagellum and toxin phase variation and impacts virulence in Clostridioides difficile

The intestinal pathogen Clostridioides difficile exhibits heterogeneity in motility and toxin production. This phenotypic heterogeneity is achieved through phase variation by site-specific recombination via the DNA recombinase RecV, which reversibly inverts the “flagellar switch” upstream of the flg...

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Detalles Bibliográficos
Autores principales: Trzilova, Dominika, Anjuwon-Foster, Brandon R., Torres Rivera, Dariana, Tamayo, Rita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446863/
https://www.ncbi.nlm.nih.gov/pubmed/32785266
http://dx.doi.org/10.1371/journal.ppat.1008708