Cargando…

Partitioning gene-based variance of complex traits by gene score regression

The majority of genome-wide association studies (GWAS) loci are not annotated to known genes in the human genome, which renders biological interpretations difficult. Transcriptome-wide association studies (TWAS) associate complex traits with genotype-based prediction of gene expression deriving from...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Wenmin, Li, Si Yi, Liu, Tianyi, Li, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446906/
https://www.ncbi.nlm.nih.gov/pubmed/32817676
http://dx.doi.org/10.1371/journal.pone.0237657